Andrea Cara obtained his PhD from the University of Cagliari, Italy. He performed his training at the National Institutes of Health (Bethesda, MD, USA) and he held an Assistant Professor position at The Mount Sinai Medical School (New York, NY, USA). He currently is a researcher in the National Center for Global Health at the Istituto Superiore di Sanità (Roma, Italy) and holds a research scholar faculty position in the Department of Medicine at Duke University (Durham, NC, USA). He has been working in the field of molecular virology for many years with a major expertise in developing Integrase Defective Lentiviral Vectors (IDLV) as antigen delivery systems in murine and non-human primate model systems against infectious diseases, including HIV, Influenza and HPV, and to different cell types, including cell lines and primary cells. He devised new IDLVs leading to the first demonstration that IDLV are a safe and suitable delivery system for immunization in prophylactic and therapeutic approaches in murine model systems, and for immunization in prophylactic approaches in the non-human primate model of immunization by using HIV Envelope. He is involved in several national and international projects as PI or Co-PI. Over the past years, he has supervised the work of several students and post docs.